Gene transfer and expression in mammalian cells
This volume provides a broad, state-of-the-art coverage of diverse technical topics in gene expression in mammalian cells, including the development of vectors for production of proteins in cultured cells, in transgenic animals, vaccination, and gene therapy; progress in methods for the transfer of genes into mammalian cells and the optimization and monitoring of gene expression; advances in our understanding and manipulation of cellular biochemical pathways that have a quantitative and qualitative impact on mammalian gene expression; and the large-scale production and purification of proteins from cultured cells
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Why choose mammalian cells for protein production? / Savvas C. Makrides, Holly L. Prentice
Vectors for gene expression in mammalian cells / Savvas C. Makrides
Virus-based vectors for gene expression in mammalian cells. Herpes simplex virus / Edward A Burton, Qing Bai, William F. Goins, David J. Fink, Joseph C. Glorioso
Virus-based vectors for gene expression in mammalian cells. Epstein-Barr virus / Gregory Kennedy, Bill Sugden
Virus-based vectors for gene expression in mammalian cells. SV40 / David S. Strayer, Pierre Cordelier, Julien Landré, Alexei Matskevitch, Hayley J. McKee, Carmen N. Nichols, Martyn K. White, Marlene S. Strayer
Virus-based vectors for gene expression in mammalian cells. Adeno-associated virus / Xiao Xiao
Virus-based vectors for gene expression in mammalian cells. Adenovirus / Denis Bourbeau, Yué Zeng, Bernard Massie
Virus-based vectors for gene expression in mammalian cells. Vaccinia virus / Miles W. Carroll, Gerald R. Kovacs
Virus-based vectors for gene expression in mammalian cells. Baculovirus / J. Patrick Condreay, Thomas A. Kost
Virus-based vectors for gene expression in mammalian cells. Coronavirus / Luis Enjuanes, Fernando Almazán, Javier Ortego
Virus-based vectors for gene expression in mammalian cells. Poliovirus / Shane Crotty, Raul Andino
Virus-based vectors for gene expression in mammalian cells. Sindbis virus / Henry V. Huang, Sondra Schlesinger
Virus-based vectors for gene expression in mammalian cells. Semliki Forest virus / Kenneth Lundstrom
Virus-based vectors for gene expression in mammalian cells. Retrovirus / Cristina Parolin, Giorgio Palù
Virus-based vectors for gene expression in mammalian cells. Lentiviruses / Mehdi Gasmi, Flossie Wong-Staal
Methods for DNA introduction into mammalian cells / Pamela A. Norton, Catherine J. Pachuk
Lipid reagents for DNA transfer into mammalian cells / Christophe Masson, Virginie Escriou, Michel Bessodes, Daniel Scherman
Reporter genes for monitoring gene expression in mammalian cells / Jawed Alam, Julia L Cook
Gene transfer and gene amplification in mammalian cells / Florian M. Wurm, Martin Jordan
Co-transfer of multiple plasmids/viruses as an attractive method to introduce several genes in mammalian cells / Martin Jordan, Florian M. Wurm
Optimization of plasmid backbone for gene expression in mammalian cells / Pascal Bigey, Marie Carrière, Daniel Scherman
Use of scaffold/matrix-attachment regions for protein production / Pierre-Alain Girod, Nicolas Mermod
Chromatin insulators and position effects / David W. Emery, Mari Aker, George Stamatoyannopoulos
Locus control regions / Xiangdong Fang, Kenneth R. Peterson, Qiliang Li, George Stamatoyannopoulos
Protein synthesis, folding, modification, and secretion in mammalian cells / M. Stacey Arnold, Randal J. Kaufman
Pathways and functions of mammalian protein glycosylation / Dale A. Cumming
Metabolic engineering of mammalian cells for higher protein yield / Hitto Kaufmann, Martin Fussenegger
Translational regulation in mammalian cells / Marilyn Kozak
Pathways of mammalian messenger RNA degradation / Angela Inácio, Stephen A. Liebhaber
Pathways of mammalian protein degradation / William A. Dunn Jr
Stabilization of proteasomal substrates by viral repeats / Nico P. Dantuma, Maria G. Masucci
Architecture and utilization of highly expressed genomic sites / Jürgen Bode, Sandra Götze, Ellen Ernst, Yves Hüsemann, Alexandra Baer, Jost Seibler, Christian Mielke
Intracellular targeting of antibodies in mammalian cells / Quan Zhu, Wayne A. Marasco
Inducible gene expression in mammalian cells / Wilfried Weber, Martin Fussenegger
Protein production by large-scale mammalian cell culture / Liangzhi Xie, Weichang Zhou, David Robinson
Protein production in transgenic animals / Yann Echelard, Harry M. Meade
Strategies for the purification of recombinant proteins / Steven L. Giardina
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